Analgesia induced by morphine microinjection into and electrical stimulation of the nucleus reticularis paragigantocellularis of rat medulla oblongata
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چکیده
منابع مشابه
Analgesic effect of electrical stimulation and microinjection of L-glutamate into the paragigantocellularis nucleus on phasic and tonic pain
The paragigantocellularis (PGi) nucleus constitutes a large portion of the ventral pontomedullary reticular formation. Neurons within the PGi have been implicated in a variety of functions including cardiovascular regulation, respiratory control, pain and analgesia. Investigators have demonstrated that electrical stimulation and microinjection of L-glutamate into the PGi produce antinocicepti...
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In the present study, the effect of contralateral and bilateral electrolytic lesions of the nucleus reticularis paragigantocellularis (PGi) on tonic pain was assessed in rats. Pain-related behavior was evaluated using the formalin test 7 days after the lesion was made. PGi lesions did not produce any marked changes in the early phase of the formalin test, but significantly increased pain sens...
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ژورنال
عنوان ژورنال: Japanese Journal of Pharmacology
سال: 1978
ISSN: 0021-5198
DOI: 10.1016/s0021-5198(19)67094-0